1. which of the following is the only Black Box Warning associated with the medication atomoxetine?

Increased risk for cardiovascular events

Suicidal ideation

Substance abuse potential

Slight growth inhibition

Which medication below would you use in addition to benzodiazepine treatment if the patient is experiencing psychosis during alcohol withdrawal delirium?

Naltrexone

Haloperidol

Propofol

Chlordiazepoxide

Question 3

Which club drug is structurally similar to GABA?

3,4 – methylendedioxy-methamphetamine

Ketamine

γ-hydroxybutyrate

Ecstasy

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Question 4

Benzodiazepines can be withdrawn abruptly despite duration of therapy/abuse.

True

False

Question 5

Disulfiram has been proven effective in the treatment of alcoholism, but recently it has been trialed in the management of cocaine addiction. What is the mechanism of action that likely helps produce these aversive effects?

Inhibition on dopamine beta-hydroxylase

Inhibition on aldehyde dehydrogenase

Inhibition on alcohol dehydrogenase

Inhibition on aldehyde reductase

Question 6

T. K. is a 72-year-old female who has suffered many strokes in the past, likely due to uncontrolled hypertension and hyperlipidemia. She has now been diagnosed with vascular dementia due to memory loss and motor system slowing. What is the recommended treatment for T. K.?

T. K. needs the drug donepezil to help with her memory loss only.

T. K. needs the drug donepezil to help with her memory loss, but also needs her hypertension and hyperlipidemia controlled.

T. K. needs the drug donepezil to help with her memory loss, but also needs her hypertension controlled.

T. K. needs her hypertension controlled only.

Question 7

Which of the following drugs in the treatment of Alzheimer’s Disease requires administration with food?

Memantine

Donepezil

Rivastigmine

Galantamine

Question 8

Which features are consistent with delirium?

I. Acute onset

II. Gradual onset

III. Course of disease fluctuates

IV. Course of diseases does not fluctuate

V. Impaired attention

VI. Normal attention

II, IV, and VI

I and III

II and IV

I, III, and V

Question 9

When can buprenorphine be initiated in a patient who is suffering from an opioid overdose?

As soon as the patient is stabilized

It should be administered as soon as you find the patient unconscious

Right after naloxone is administered to prevent the patient from going back into opioid overdose

When the patient is experiencing mild-to-moderate symptoms of withdrawal

Question 10

Y. R. is a 35-year-old woman who presents to your clinic today complaining of ankle pain. She said she was running the trail when she saw a snake. During a quick turn to run away from the snake, she twisted her ankle. Which of the following medications may be a good choice in helping Y. R. with her pain?

Oxycodone

Amitriptyline

Ibuprofen

Duloxetine

Question 11

Which of the following drugs in the treatment of Alzheimer’s Disease helps normalize glutamate by antagonizing the NMDA receptor?

Memantine

Donepezil

Rivastigmine

Galantamine

Question 12

Choose the correct statement regarding an anti-ADHD medication and its respectful mechanism of action

Methylphenidate – blocks reuptake of dopamine in the pre-synaptic neuron and promotes release of dopamine from their storage sites in the pre-synaptic neuron

Amphetamines – blocks reuptake of norepinephrine and dopamine into presynaptic neurons

Clonidine – blocks reuptake of dopamine in the pre-synaptic neuron and promotes release of dopamine from their storage sites in the pre-synaptic neuron

Atomoxetine – acts by blocking the norepinephrine pump on the pre-synaptic membrane

Guanfacine – blocks reuptake of norepinephrine and dopamine into presynaptic neurons

Question 13

Drug addiction includes many prescription medications and illegal substances. Of the drugs listed, which ones can be withdrawn abruptly WITHOUT medical intervention to prevent withdraw seizures?

Alcohol

Adderall

Lorazepam

Butalbital

Question 14

Select the correct description of a somatoform disorder.

Somatization disorder – manifests as a pain syndrome with a significant loss of or alteration in physical function that mimics a physical disorder

Conversion disorder – pain that causes significant impairment in occupation or social function, induces marked distress, or both

Hypochondriasis – persistent belief that one has a serious illness, despite extensive medical evaluation

Pain disorder – intentional production or feigning of physical symptoms

Question 15

If a patient suffers from a multitude of small strokes and later begins experiencing mood disturbances in an acute fashion that sometimes resolve, from what type of dementia would you think that patient may suffer?

Vascular Dementia

Frontotemporal Dementias

Alzheimer’s Disease

Dementia with Lewy Bodies

Question 16

What is the difference between Ritalin and Focalin?

Focalin is a D-isomer

Ritalin is the D-isomer

Focalin is the S-isomer

There is no difference other than the formulations involved.

Question 17

Choose the correct statement regarding medications used for alcoholism

Disulfiram: NMDA receptor antagonist & GABAA agonist

Naltrexone: µ-opioid receptor antagonist that reduces the reinforcement/euphoria produced by alcohol

Acamprosate: enhances the effect of the inhibitory neurotransmitter gamma-aminobutyric acid on the GABA receptors by binding to a site that is distinct from the GABA binding site in the central nervous system.

Lorazepam: inhibits alcohol dehydrogenase, leading to a buildup of acetaldehyde

Question 18

Patient is a 10-year-old female with diagnosed ADHD who was started on Ritalin 5 mg twice a day over 2 months ago. She is still experiencing the triad of symptoms associated with ADHD (impaired attention, impulsivity, and excessive motor activity). Her mother reports that she is now having difficulty in falling asleep since starting the medication. She has been on no other anti-ADHD medications and the mother reports full compliance with medication regimen. What is the appropriate recommendation to make based on this scenario?

Recommend psychotherapy in addition to current treatment

Switch to low dose Focalin

Add Clonidine

Switch to low-dose Adderall and titrate as appropriate in addition to psychotherapy

Question 19

Of the axons involved in the transmission of pain, which one is thinly myelinated and conducts that first feeling of pain that is often felt as coming on as a sharp, rapid feeling?

ß-∆ fibers

A-∆ fibers

A-ß fibers

C fibers

Question 20

Of the following neurotransmitters, which one(s) are known to be severely disrupted in the disease Dementia with Lewy Bodies?

I. Acetylcholine

II. Glutamate

III. Dopamine

IV. GABA

V. Norepinephrine

II only

III only

I and II

I and III

Question 21

Which of the following drugs is structurally similar to tramadol; thus, its opioid-mediated analgesia can be reversed by naloxone in mice?

Venlafaxine

Ketorolac

Duloxetine

Gabapentin

Question 22

Which medication is a selective alpha-adrenergic agonist that works by mimicking norepinephrine binding in the pre-frontal cortex, which makes it particularly useful in the treatment of ADHD?

Guanfacine

Modafinil

Lisdexamfetamine

Bupropion

Question 23

Which of the following psychiatric conditions is present in both domains (i.e., core psychopathology & pain-related psychological symptoms) of chronic pain that will likely lead to an outcome of disability, pain, and poor quality of life?

Major depression

Personality disorder

Anger

Anxiety

Question 24

What baseline levels should you perform before initiating an anti-ADHD medication?

Electrolytes, height, weight, white-blood cells

ECHO, heart rate, pulse

Height, weight, blood pressure, pulse

Blood pressure and pulse

Question 25

Which of the following alcohol screening tools lack sensitivity to detect hazardous/problem drinking?

AUDIT

AUDIT-C

SASQ

CAGE

Question 26

There are many different types of dementia. Which dementia is NOT a direct result of disrupted neurotransmitters, but a result of degeneration of different regions in the brain? Onset of the disease is typically before the age of 60, and very rare after the age of 75.

Alzheimer’s Disease

Dementia with Lewy Bodies

Creutzfeldt-Jakob Disease

Frontotemporal Dementias

(SOLVED) QUIZ – Black box warning Nursing

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